Medical References
Peer-reviewed medical research relevant to the conditions we treat and the hyperbaric oxygen therapy protocol we use.
Restor Neurol Neurosci · 2020; 38(1):93-107
Hyperbaric oxygen therapy improves neurocognitive functions of post-stroke patients: a retrospective analysis
Amir Hadanny, Mor Rittblat, Mor Bitterman, Ido May-Raz, Gil Suzin, Rahav Boussi-Gross, Yonatan Zemel, Yair Bechor, Merav Catalogna, Shai Efrati
J Med Case Rep · 2025; 19: 493
Anatomical and metabolic brain imaging correlation of neurological improvements following hyperbaric oxygen therapy: post-stroke recovery: a case report
Sherif Khairy, Mouzayan Ginzarly, Zemer Wang, et al.
Scientific Reports (Nature) · March 2022
Persistent post-concussive syndrome in children after mild traumatic brain injury is prevalent and vastly underdiagnosed
Eli Fried, Uri Balla, Merav Catalogna, Eran Kozer, Adi Oren-Amit, Amir Hadanny, Shai Efrati
BMJ Open · 2018; 8(9): e023387
Effect of Hyperbaric Oxygen Therapy on Chronic Neurocognitive Deficits of Post-Traumatic Brain Injury Patients: Retrospective Analysis
Hadanny, A., S. Abbott, G. Suzin, Y. Bechor, and S. Efrati
PLoS One · 2013; 8(11): e79995
Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Traumatic Brain Injury: Randomized Prospective Trial
Boussi-Gross, R., H. Golan, G. Fishlev, Y. Bechor, O. Volkov, J. Bergan, M. Friedman, D. Hoofien, N. Shlamkovitch, E. Ben-Jacob, and S. Efrati
J Pediatr Neurosci · 2012; 7(1):4-8
Role of hyperbaric oxygen therapy in severe head injury in children
Advait Prakash, Sandesh V. Parelkar, Sanjay N. Oak, Rahul K. Gupta, Beejal V. Sanghvi, Mitesh Bachani, Rajashekhar Patil
PLoS One · 2013; 8(1): e53716
Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients: Randomized, Prospective Trial
Efrati, S., G. Fishlev, Y. Bechor, O. Volkov, J. Bergan, K. Kliakhandler, I. Kamiager, N. Gal, M. Friedman, E. Ben-Jacob, and H. Golan
Scientific Reports (Nature) · 2022; 12: 15233
Hyperbaric oxygen therapy in children with post-concussion syndrome improves cognitive and behavioral function: a randomized controlled trial
Amir Hadanny, Merav Catalogna, Slava Yaniv, Orit Stolar, Lynn Rothstein, Adi Shabi, Gil Suzin, Efrat Sasson, Erez Lang, Shachar Finci, Nir Polak, Gregory Fishlev, Ruth Tock Harpaz, Moran Adler, Ron-El Goldman, Yonatan Zemel, Yair Bechor and Shai Efrati
Frontiers in Neurology · 2025; 16: 1641033
Hyperbaric oxygen therapy improves post-concussion symptoms in adults with childhood traumatic brain injury: a retrospective cohort study
Shifler AS, Suzin G, Shorer R, Lang E, Finci S, Elman-Shina K, Doenyas-Barak K, Efrati S
Expert Review of Neurotherapeutics · June 2025
Persistent post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies
Amir Hadanny, Shai Efrati
Gavin Publishers · December 2023
Chronic Traumatic Encephalopathy, Traumatic Encephalopathy Syndrome, Post-Concussion Syndrome, and the Therapeutic Potential of Hyperbaric Oxygen Therapy: A Comprehensive Case Study and Discussion
Zemer Wang, Sherif Khairy, Umair Qureshi, et al.
Scientific Reports (Nature) · 2022; 12: 11252
Hyperbaric oxygen therapy improves neurocognitive functions and symptoms of post-COVID condition: randomized controlled trial
Shani Zilberman-Itskovich, Merav Catalogna, Efrat Sasson, Karin Elman-Shina, Amir Hadanny, Erez Lang, Shachar Finci, Nir Polak, Gregory Fishlev, Calanit Korin, Ran Shorer, Yoav Parag, Marina Sova, Shai Efrati
Scientific Reports (Nature) · 2023; 13: 9473
The effect of hyperbaric oxygen therapy on myocardial function in post-COVID-19 syndrome patients: a randomized controlled trial
Marina Leitman, Shmuel Fuchs, Vladimir Tyomkin, Amir Hadanny, Shani Zilberman-Itskovich, Shai Efrati
Scientific Reports (Nature) · 2024; 14: 3604
Long term outcomes of hyperbaric oxygen therapy in post covid condition: longitudinal follow-up of a randomized controlled trial
Amir Hadanny, Shani Zilberman-Itskovich, Merav Catalogna, Karin Elman-Shina, Erez Lang, Shachar Finci, Nir Polak, Ran Shorer, Yoav Parag, Shai Efrati
PLoS One · 2015; 10(5): e0127012
Hyperbaric Oxygen Therapy Can Diminish Fibromyalgia Syndrome: Prospective Clinical Trial
Efrati, S., H. Golan, Y. Bechor, Y. Faran, S. Daphna-Tekoah, G. Sekler, G. Fishlev, J. N. Ablin, J. Bergan, O. Volkov, M. Friedman, E. Ben-Jacob, and D. Buskila
PLoS One · 2023; 18(3): e0282406
Hyperbaric oxygen therapy compared to pharmacological intervention in fibromyalgia patients following traumatic brain injury: A randomized, controlled trial
Jacob N. Ablin, Erez Lang, Merav Catalogna, Valerie Aloush, Amir Hadanny, Keren Doenyas-Barak, Shachar Finci, Nir Polak, Gregory Fishlev, Calanit Korin, Rachel Yehudit Tzidky, Oshra Meir Genuth, Shai Efrati
Scientific Reports (Nature) · May 2024
Hyperbaric oxygen therapy vs. pharmacological intervention in adults with fibromyalgia related to childhood sexual abuse: prospective, randomized clinical trial
Rahav Boussi-Gross, Merav Catalogna, Erez Lang, Zipora Shamai, Jacob N. Ablin, Valerie Aloush, Keren Doenyas-Barak, Mordechai Lorberboym, Rachel Lev-Wiesel, Shai Efrati
Aging · September 2021
The effect of hyperbaric oxygen therapy on the pathophysiology of skin aging: a prospective clinical trial
Yafit Hachmo, Amir Hadanny, Sonia Mendelovic, Pnina Hillman, Eyal Shapira, Geva Landau, Hadar Gattegno, Avi Zrachya, Malka Daniel-Kotovsky, Merav Catalogna, Gregory Fishlev, Erez Lang, Nir Polak, Keren Doenyas, Mony Friedman, Yonatan Zemel, Yair Bechor, Shai Efrati
Aging · October 2021
Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial
Yafit Hachmo, Amir Hadanny, Ramzia Abu Hamed, Malka Daniel-Kotovsky, Merav Catalogna, Gregory Fishlev, Erez Lang, Nir Polak, Keren Doenyas, Mony Friedman, Yonatan Zemel, Yair Bechor, Shai Efrati
Aging · September 2021
Hyperbaric oxygen therapy alleviates vascular dysfunction and amyloid burden in an Alzheimer's disease mouse model and in elderly patients
Ronit Shapira, Amos Gdalyahu, Irit Gottfried, Efrat Sasson, Amir Hadanny, Shai Efrati, Pablo Blinder, Uri Ashery
Biomolecules · 2020; 10(9): 1328
Oxygen: The Rate-Limiting Factor for Episodic Memory Performance, Even in Healthy Young Individuals
Gil Suzin, Tom Halpert Frolinger, Dror Yogev, Amir Hadanny, Merav Catalogna, Yuri Rassovsky, Shai Efrati
Biomolecules · 2021; 11(10): 1520
Hyperbaric Oxygen Treatment: From Mechanisms to Cognitive Improvement
Irit Gottfried, Nofar Schottlender and Uri Ashery
Biomolecules · 2021; 11(12): 1827
Hyperbaric Oxygen Treatment: Effects on Mitochondrial Function and Oxidative Stress
Nofar Schottlender, Irit Gottfried and Uri Ashery
J Chin Med Assoc · 2014; 77(5): 269-71
Hyperbaric oxygen therapy as an effective adjunctive treatment for chronic Lyme disease
Chien-Yu Huang, Yen-Wen Chen, Tseng-Hui Kao, Hsin-Kuo Kao, Yu-Chin Lee, Jui-Chun Cheng, Jia-Horng Wang
Ann Neurol · 2012; 72(5): 695-703
Effects of hyperbaric oxygen on motor function in children with cerebral palsy
Daniel J. Lacey, Adrienne Stolfi, Louis E. Pilati
The Lancet · June 2001
Hyperbaric oxygenation for cerebral palsy
R. A. Neubauer
Lancet · 2001; 357(9256): 582-6
Hyperbaric oxygen for children with cerebral palsy: a randomised multicentre trial. HBO-CP Research Group
Jean-Paul Collet, Michel Vanasse, Pierre Marois, Maxime Amar, Joanne Goldberg, Jean Lambert, Maryse Lassonde, Paule Hardy, Josée Fortin, Stéphane D Tremblay, David Montgomery, Jacques Lacroix, Ann Robinson, Annette Majnemer, and the HBO-CP Research Group
Dev Med Child Neurol · 2002; 44(7): 436-46
Neuropsychological effects of hyperbaric oxygen therapy in cerebral palsy
Paule Hardy, Jean-Paul Collet, Joanne Goldberg, Thierry Ducruet, Michel Vanasse, Jean Lambert, Pierre Marois, Maxime Amar, David L Montgomery, Jacqueline M Lecomte, Karen M Johnston, Maryse Lassonde
Undersea Hyperb Med · 2014; 41(2): 77-85
Intensive rehabilitation combined with HBO2 therapy in children with cerebral palsy: A controlled longitudinal study
Arun Mukherjee, Maxime Raison, Tarun Sahni, Anand Arya, Jean Lambert, Pierre Marois, Philip B. James, Audrey Parent, Laurent Ballaz
Complement Med Res · 2022; 29(2): 158-171
Hyperbaric Oxygen Therapy Is Beneficial for the Improvement of Clinical Symptoms of Cerebral Palsy: A Systematic Review and Meta-Analysis
Yingqian Zhang, Jing Wu, Nong Xiao, Bo Li
ResearchGate · March 2014
How and why hyperbaric oxygen therapy can bring new hope for children suffering from cerebral palsy: an editorial perspective
Shai Efrati, Eshel Ben-Jacob
BMC Pediatrics · 2007; 7: 36
The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: an open-label pilot study
Daniel A Rossignol, Lanier W Rossignol, S Jill James, Stepan Melnyk, Elizabeth Mumper
Int J Mol Sci · 2022; 23(19): 11077
Hyperbaric Oxygen Therapy Alleviates Social Behavior Dysfunction and Neuroinflammation in a Mouse Model for Autism Spectrum Disorders
Inbar Fischer, Sophie Shohat, Gilad Levy, Ela Bar, Sari Schokoroy Trangle, Shai Efrati, Boaz Barak
Cureus · 2024; 16(1): e51654
The Effects of Hyperbaric Oxygen Treatment on Verbal Scores in Children With Autism Spectrum Disorder: A Retrospective Trial
Tami Peterson, Robert Sherwin, Tiffany Hosey, Nicole Close, Frederick Strale Jr
Looking for press coverage and interviews? Visit our Press & Media page. For articles from our clinicians, see the Knowledge Centre.